No benefit to increasing dose intensity of chemotherapy in osteosarcoma,...
A dose-intensive regimen of the chemotherapy drugs cisplatin and doxorubicin offered no clinical benefit over standard doses of the chemotherapy drugs in patients with a bone cancer called...
View ArticleChildhood cancer survivors at increased risk of sarcoma
Survivors of childhood cancers have a ninefold increased risk of developing a secondary sarcoma—a cancer of connective or supportive tissue such as bone, fat, or muscle—compared with the general...
View ArticleInsights into osteosarcoma in cats and dogs may improve palliative care
Researchers at the University of Illinois have found that a molecular pathway known to have a role in the progression of bone cancer in humans is also critical to the pathology of skeletal tumors in...
View ArticleResearchers find that childhood sarcoma increases risk of blood clots
Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have determined that children and young adults with a form of cancer called sarcoma are at increased risk...
View ArticleStudy shows drug effective in treating, preventing breast cancer
A new study of an estrogen-derived drug shows promise as a treatment for breast cancer and breast cancer metastases to bone. (2007-11-01)
View ArticleSame process discovered to both form skeleton and protect it for life
A protein signaling pathway recently discovered to guide the formation of the skeleton in the fetus also keeps bones strong through adult life, according to two papers published recently in the journal...
View ArticleNovel model of osteosarcoma
In the June 15th issue of G&D, Dr. Stuart Orkin (HHMI, Dana-Farber Cancer Institute, Children's Hospital Boston) and colleagues present a new mouse model of osteosarcoma. (2008-06-16)
View ArticleResearchers identify potential therapeutic target in osteosarcoma
A receptor known to be active in bone metastases, but previously unexplored in primary bone tumors, is a potential therapeutic target in osteosarcoma, investigators from The University of Texas M. D....
View ArticleMU Veterinary Oncologists Advance Cancer Drugs for Humans and Pets
As more pet owners are choosing to treat their pets' cancers through advanced medicine, veterinarians gain valuable knowledge about the progression and treatment of cancers in humans through pet trials...
View ArticleA longer lasting tumor blocker
On the heels of dismaying reports that a promising antitumor drug could, in theory, shorten patients' long-term survival, comes a promising study by a Japanese team of researchers that suggests a...
View ArticleNew strategy in tumor treatment
A new strategy proposed by researchers at Dartmouth Medical School and Amtek, Hanover, NH may treat tumors that do not respond to conventional treatment. (2009-07-20)
View ArticleStudying cancer in pet dogs to find new treatments for human patients
A team of scientists at the National Cancer Institute (NCI) in Bethesda, USA, says that studying pet dogs with cancer could yield valuable information on how to diagnose and treat human cancers....
View ArticleApproved lymphoma drug shows promise in early tests against bone cancer
A drug already approved for the treatment of lymphoma may also slow the growth of the most deadly bone cancer in children and teens, according to an early-stage study published online today in the...
View ArticleSlobbery kisses from 'man's best friend' aid cancer research
Fido's wet licks might hold more than love. They could provide the DNA keys to findings new treatments for rare cancers and other diseases in both dogs and human patients. (2010-04-15)
View ArticleResearchers find pathway that drives spread of pediatric bone cancer in...
Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer. (2010-10-26)
View ArticleResearcher develops accurate method for detecting dangerous fluoride
Used in the proper amounts, it can make teeth stronger and aid in the treatment of osteoporosis. (2010-12-10)
View ArticleMount Sinai researchers discover possible new target for sarcoma treatment...
Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may...
View ArticleStudy shows bone fluoride levels not associated with osteosarcoma
The International and American Associations for Dental Research have released in its Journal of Dental Research a study that investigated bone fluoride levels in individuals with osteosarcoma, which is...
View ArticleBuilding bone from cartilage
A person has a tumor removed from her femur. A soldier is struck by an improvised explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone...
View ArticleNovel surgery removes rare tumor, rebuilds face and jaw
Using a novel surgical approach, it's possible to rebuild a functional lower jaw and mouth, and preserve a patient's ability to eat and speak after removing an invasive facial tumor, according to a new...
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